The faster the game moves, the shorter the time to sideline, and the less time you have to make the pitch. At some point, even if the defense and offense both increase at speed equally, there simply won't be enough time to make the pitch to run the offense effectively. And while finance IS one of the reasons an option wouldn't be viable in the NFL, it's not the only reasons, because the Falcons did in fact run one with Vick. Like I said, it worked for a couple games, but then it just became completely unproductive. All the analysts seemed to know it was going to happen that way, too.
This is a funny statement, as Vick's rushing numbers generally increased throughout his career.
2001: 8 games/289 yards/9.3 avg.
2002: 15 games/777 yards/6.9 avg.
2003: 5 games/255 yards/6.4 avg.
2004: 15 games/902 yards/7.5 avg.
2005: 15 games/597 yards/5.9 avg.
2006: 16 games/1039 yards/8.4 avg.
But the Falcons weren't running the option. Bad comparison, IMO.
Option ball is predicated on removing players, and gaining the advantage, on the play side by forcing them to commit first, creating gaps, and then pushing the ball past them. You can option a pro player as well as a college player, but pro players will pursue faster and cover the gap quicker, making it more difficult to make the large gains that are possible in college ball. The gains you do make will not be worth the wear and tear on your franchise QB. Further, the quality of DB's in the pro game will allow far more man coverage, thus negating the advantage gained in college ball from forcing a DB into constant run support.
In short, option ball would work in the NFL, but the not hardly more than the typical pro-set, and it will put your most critical player at a huge risk.
There are 32 NFL teams in the NFL, 120 D1A teams in college. QB's play for an average of about 14 seasons, for college it's about 3 seasons. Finding and keeping a solid pro-set quality QB is much less difficult in the NFL than it is in college. This is a major driver for colleges running some form of run-based offense. It is not easy to find the QB in college every 3 years who can run your pro-set the way it needs to be run. There are far more 6'0" fast, athletic guys who can run a college option offense than there are 6'4" future Dan Marino's out there in high schools today.